Musculoskeletal Disorders

Course Instructor: Pharm Prep

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Module Overview

Sub-Modules

1 Subject

Musculoskeletal

4 Exercises • 71 Learning Materials

Osteoporosis

Introduction

Investigations

Risk Factors - Prompting Assessment for Osteoporosis (Measurement of BMD)

Fracture Risk Assessment Tool (FRAX)

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CAROC System: - Predict 10-Year Fragility Fracture Risk

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Nonpharmacologic Choices

Pharmacologic Choices

Table - Nutritional Supplements in Osteoporosis Management

Bisphosphonates

Drug Table - Bisphosphonates

Bisphosphonate Drug Holidays

Table - Bisphosphonates Drug Holiday Recommendations

RANK Ligand Inhibitors

Table - RANK Ligand Inhibitor – Denosumab

Selective Estrogen Receptor Modulators

Table - Selective Estrogen Receptor Modulators (SERMs)

Estrogen and Progesterone

Calcitonin

Table - Calcitonin Peptides

Parathyroid Hormone, Parathyroid Hormone-Related Peptide and Analogues

Table - Anabolic Agents

Romosozumab

Drug Table - Romosozumab

Strontium Ranelate

Combination Therapies

Corticosteroid-Induced Osteoporosis

Treatment - Osteoporosis in Patients with Chronic Kidney Disease

Algorithm - Bone Density, FRAX- or CAROC-Calculated 10-Year Fracture Risk in Osteoporosis Management

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Osteoporosis

Exercise

Rheumatoid Arthritis

Introduction

Investigations

Classification Criteria - Rheumatoid Arthritis

Baseline Evaluation - Disease Activity and Damage

Nonpharmacologic Choices

Pharmacologic Choices

Poor Prognostic Factors for Rheumatoid Arthritis

Conventional Synthetic Disease-Modifying Antirheumatic Drugs

Table - Conventional Synthetic Disease-Modifying Antirheumatic Drugs for RA

Biologic Disease-Modifying Antirheumatic Drugs

Table - Biologic DMARDs for RA

Targeted Synthetic DMARDs (tsDMARDs)

Table - Targeted Synthetic DMARDs

Discontinuation / Dosage Reduction of Biologic DMARDs

Safety - Biologic and Targeted Synthetic DMARDs

Recommendations - Vaccination in Patients with Rheumatoid Arthritis

Nonsteroidal Anti-inflammatory Drugs

Corticosteroids

Analgesia

Choices during Pregnancy

Algorithm - Management of Rheumatoid Arthritis

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Rheumatoid Arthritis

Exercise

Gout & Hyperuricemia

Introduction

Asymptomatic Hyperuricemia

Drugs / Conditions Associated with Hyperuricemia and Gout

Gouty Flare

Gouty Flare - Therapeutic Choices

The ACR-EULAR Gout Classification Criteria

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Algorithm - Treatment of Acute Gout

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Intercritical Gout

Intercritical Gout - Therapeutic Choices

Algorithm - Treatment of Hyperuricemia

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Chronic Tophaceous Gout

Table - Drugs Used in the Management of Gout

Gout & Hyperuricemia

Exercise

Systemic Lupus Erythematosus (SLE)

Introduction

Autoantibodies in SLE

Investigations

EULAR / ACR - SLE classification criteria

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Nonpharmacologic Choices

Pharmacologic Choices

Drug-Induced Lupus Erythematosus

Choices during Pregnancy and Breastfeeding

Table - Drugs Used in SLE

Algorithm - Treatment of Systemic Lupus Erythematosus

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Systemic Lupus Erythematosus (SLE)

Exercise