Neurologic Disorders

Course Instructor Pharm Prep

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Module Overview

Sub-Modules

1 Subject

Neuro

7 Exercises • 148 Learning Materials

Parkinson's Disease

Introduction

Investigations

Nonpharmacologic Choices

Pharmacologic Choices

Drug Therapy Based on Parkinson Disease Progression

Treatment of Nonmotor Issues

Algorithm - Pharmacologic Management of Parkinson Disease

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Algorithm - Management of Levodopa-Associated Motor Complications

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Drug Table - Levodopa Preparations

Drug Table - Dopamine Agonists

Drug Table - Monoamine Oxidase B Inhibitors

Drug Table - N-Methyl-D-Aspartate (NMDA) Receptor Antagonists

Drug Table - Catechol-O-Methyl Transferase (COMT) Inhibitors

Drug Table - Anticholinergic Agents

Parkinson's Disease

Exercise

Alzheimer's Disease

Introduction

Common Dementia Types and Their Presentation

Stages of Dementia

Investigations

Medications That May Contribute to Dementia or Cognitive Impairment

Nonpharmacologic Choices

Pharmacologic Choices

Cholinesterase Inhibitors

N-methyl-D-aspartate Receptor Antagonists

Other Therapies

Responsive Behaviors in Dementia

Pharmacologic Choices

Prevention of Dementia

Algorithm - Management of Newly Diagnosed Dementia

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Drug Table - Cholinesterase Inhibitors

Drug Table - N-methyl-D-aspartate Receptor Antagonists

Drug Table - Antipsychotics

Drug Table - Serotonergic Antidepressants

Alzheimer's Disease

Exercise

Seizures & Epilepsy

Introduction

Investigations

Clinical Features of Common Epileptic Seizure Types

Nonpharmacologic Choices

Pharmacologic Choices - Suggested Therapeutic Options

Basic principles for initiating ASM therapy

Management of Convulsive Status Epilepticus in Adults

Managing - Adverse Effects of Antiseizure Medications

Discontinuing Antiseizure Medications

Contraception and Antiseizure Medications

Effect of Antiseizure Medications (ASMs) on Hormonal Contraceptive Methods

Impact of Antiseizure Medications (ASMs) on Hepatic Enzymes

Choices during Pregnancy and Breastfeeding

Algorithm - Management of Seizures and Epilepsy

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Algorithm - First-Line Pharmacological Treatment of Epileptic Seizures

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Drug Table - Barbiturates

Drug Table - Benzodiazepines

Drug Table - Carboxylic Acid Derivatives

Drug Table - Gamma Aminobutyric Acid (GABA) Derivatives

Drug Table - Hydantoin Derivatives

Drug Table - Iminostilbene Derivatives

Drug Table - Succinimide Derivatives

Drug Table - Other Antiseizure Medications

Seizures & Epilepsy

Exercise

Migraine

Introduction / Diagnostic Criteria for Common Headache Disorders

Investigations

Headache Red Flags (SNNOOP10)

ID Migraine Screening Tool

Nonpharmacologic Choices

Tension-Type Headache

Migraine - Acute Treatment

Migraine - Preventive Therapy

Indications for Preventive Treatment of Migraine

Selection of Migraine Prophylactic Therapy

Medication-Overuse Headache

Choices during Pregnancy and Breastfeeding

Pharmacological Management of Headache During Pregnancy

Algorithm - Management of Patients with Headache

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Algorithm - Migraine Preventive Therapy

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Drug Table - Analgesics

Drug Table - Calcitonin Gene-Related Peptide (CGRP) Receptor Antagonist

Drug Table - Ergot Derivatives

Drug Table - Triptans

Drug Table – Triptan / NSAID Combination

Drug Table – Angiotensin II Receptor Antagonists (ARBs)

Drug Table – Antiepileptics

Drug Table – Antihistamines

Drug Table – Beta1-adrenergic Antagonists

Drug Table – Calcitonin Gene-Related Peptide Monoclonal Antibodies (CGRP)

Drug Table – Calcitonin Gene-Related Peptide (CGRP) Receptor Antagonist

Drug Table – Calcium Channel Inhibitors / Blockers

Drug Table – N-methyl-D-aspartate Receptor Antagonists

Drug Table – Serotonin Antagonists

Drug Table – Tricyclic Antidepressants (TCAs)

Drug Table – Natural Health Products

Migraine

Exercise

Pain

Introduction - Acute Pain

Investigations

Nonpharmacologic Choices

Oral Analgesics

Parenteral Analgesics

Topical and Local Anesthesia

Inhalation Pain Management

Choices during Pregnancy and Breastfeeding

Algorithm - Management of Acute Pain

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Drug Table - Analgesics for the Treatment of Acute Pain

Introduction - Neuropathic Pain

Types of Neuropathic Pain

Definitions Related to Neuropathic Pain

Investigations

Nonpharmacologic Choices

Pharmacologic Choices

Chronic Neuropathic Pain

Chronic Peripheral Neuropathic Pain

Nerve Root Compression: Cervical and Lumbar Radiculopathy

Complex Regional Pain Syndrome Type Ι

Acute Neuropathic Pain - Herpes Zoster

Trigeminal Neuralgia

Types of Neuropathic Pain and First-Line Treatment Options

Algorithm - Management of Chronic Peripheral Neuropathic Pain

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Guidelines for Use of Opioids in Chronic Noncancer Pain

Choices during Pregnancy and Breastfeeding

Management of the Frail Elderly

Precautions with Drugs Used to Treat Neuropathic Pain in the Elderly

Table 1 - Drug Therapy for Chronic Peripheral Neuropathic Pain

Table 2 - Drug Therapy for Chronic Peripheral Neuropathic Pain

Table - Drug Therapy for Trigeminal Neuralgia

Pain

Exercise

Sleep disorders

Introduction – Insomnia

Investigations

Sleep History

Sleep Diary

Common Comorbidities and Medications Contributing to Insomnia

Screening Tools for Key Comorbidities in Insomnia

Nonpharmacologic Choices

Sleep Hygiene Guidelines

Components of CBT-I

Targeted Cognitive Barriers to Sleep

Pharmacologic Choices

Binding Affinity of Z-drugs and Benzodiazepines

Off-Label Agents Commonly Used for Comorbid Insomnia

Natural Supplements and Over-the-Counter Agents Used for Insomnia

Special Populations

Table - Approved Medications Used to Manage Insomnia

Algorithm - Assessment and Management of Insomnia

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Sleep disorders

Exercise

Multiple Sclerosis

Introduction

Types of Multiple Sclerosis

Investigations

Nonpharmacologic Choices

Pharmacologic Choices

Risk of Infection

Disease-Modifying Therapy and Risk of Immunosuppression

Risk of Progressive Multifocal Leukoencephalopathy with MS - Therapy

Immunization

Choices during Pregnancy and Breastfeeding

Algorithm - Management of Multiple Sclerosis

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Table - First-Line Disease-Modifying Therapies for Multiple Sclerosis

Table - Second-Line Disease-Modifying Therapies for Multiple Sclerosis

Table - Adjunctive Therapy for Multiple Sclerosis

Multiple Sclerosis

Exercise